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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > EnoxoloneCAS：471-53-4
Molecular Formula：C30H46O4
Molecular Weight：470.68
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 471-53-4 |
| Name | Enoxolone |
| Molecular Formula | C30H46O4 |
| Molecular Weight | 470.68 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-444-6 |
| MDL | MFCD00003706 |
| SMILES | CC1(C)[C@@H](O)CC[C@]([C@@]1([H])CC[C@@]([C@@]2(CC[C@]3(CC[C@](C(O)=O)(C[C@]3(C2=C4)[H])C)C)C)5C)(C)[C@@]5([H])C4=O |
| InChIKey | MPDGHEJMBKOTSU-YKLVYJNSSA-N |
| InChI | InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1 |
| PubChem CID | 10114 |
| Target Point | Others |
| Passage | Others |
| Background | It is the main bioactive component of licorice with anti-ulcer, anti-inflammatory and anti-proliferative activities. |
| Biological Activity | Enoxolone是甘草的主要生物活性成分，具有抗溃疡，抗炎和抗增殖的特性。[1-3] |
| Data Literature Source | [1]. Huang RY， et al. 18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. PLoS One. 2014 Apr 2; 9 (4) :e93690. [2]. Zhou J， et al. 18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination. Sci Rep. 2015 Sep 2; 5:13713. [3]. Yang G， et al. Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats. Evid Based Complement Alternat Med. 2017; 2017:3470320. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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IF：7.9000
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PMID：30668338
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