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My Cart> Small Molecule Compounds > Anti-Infection > Anti-Bacterial > Gentamicin sulfateCAS：1405-41-0
Molecular Formula：No data available
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Appearance：White to yellow Solid
Qty：
Size：
| CAS | 1405-41-0 |
| Name | Gentamicin sulfate |
| Molecular Formula | No data available |
| Solubility | Soluble in Water ≥100mg/mL |
| Enzyme Activity/Titer | ≥590IU/mg |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 215-778-9 |
| MDL | MFCD00270181 |
| SMILES | O=S(O)(O)=O.O[C@]1(C)C(NC)[C@@H](O)[C@@H](O[C@H]2C(N)C[C@H](N)[C@@H](O[C@@H]3[C@H](N)CC[C@@H]([R])O3)[C@@H]2O)OC1.NC[*].C[C@H]([*])N.C[C@H]([*])NC.[R=].[or].[or] |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Gentamicin sulfate is an aminoglycoside antibiotic. It has good antibacterial effect on various gram-negative bacteria and gram-positive bacteria. The mechanism of action is to bind to the 30S subunit of bacterial ribosome to inhibit the synthesis of bacterial protein. |
| Biological Activity | Gentamicin sulfate是一种氨基糖苷类抗生素，抑制革兰氏阳性菌和革兰氏阴性细菌的生长并可抑制组织培养中的多种支原体菌株。抑制DNase I活性的IC50值为0.57 mM。[1-4] |
| IC50 | 0.57mM(DNase I)[1] |
| Data Literature Source | [1]. Xu W，et al. A rapid and sensitive method for kinetic study and activity assay of DNase I in vitro based on a GO-quenched hairpin probe. Anal Bioanal Chem. 2016 May;408(14):3801-9. [2]. Rudin A，et al. Antibacterial activity of gentamicin sulfate in tissue culture. Appl Microbiol. 1970 Dec;20(6):989-90. [3]. Kumar CG，et al. Microbial biosynthesis and applications of gentamicin: a critical appraisal. [4]. Espersen F，et al. Effect of treatment with methicillin and gentamicin in a new experimental mouse model of foreignbody infection. Antimicrob Agents Chemother. 1994 Sep;38(9):2047-53. |
| Unit | Bottle |
| Specification | 100mg 10mg/mL*1mL in Water 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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