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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > 3-Hydroxy-4-methoxycinnamic acidCAS：537-73-5
Molecular Formula：C10H10O4
Molecular Weight：194.18
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 537-73-5 |
| Name | 3-Hydroxy-4-methoxycinnamic acid |
| Molecular Formula | C10H10O4 |
| Molecular Weight | 194.18 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-676-0 |
| MDL | MFCD00004391 |
| SMILES | O=C(O)/C=C/C1=CC=C(OC)C(O)=C1 |
| InChIKey | QURCVMIEKCOAJU-HWKANZROSA-N |
| InChI | InChI=1S/C10H10O4/c1-14-9-4-2-7(6-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| PubChem CID | 736186 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein;Neuronal Signaling |
| Background | 3-Hydroxy-4-methoxycinnamic acid is a cinnamic acid derivative that binds and activates α1-adrenergic receptors, enhances β-endorphin secretion and increases glucose use in vitro. |
| Biological Activity | Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 μM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Isoferulic acid also has anti-influenza virus activities.[1-2] |
| Data Literature Source | [1]. Liu IM，et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204. [2]. Sakai S，et al. Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice. Mediators Inflamm. 2001 Apr;10(2):93-6. |
| Unit | Bottle |
| Specification | 20mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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