Jatrorrhizine
Cat.No:IJ0020 Solarbio
CAS:3621-38-3
Molecular Formula:C20H20NO4
Molecular Weight:338.38
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:Solid
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Neuronal Signal Pathway >
JatrorrhizineCAS:3621-38-3
Molecular Formula:C20H20NO4
Molecular Weight:338.38
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:Solid
Qty:
Size:
CAS | 3621-38-3 |
Name | Jatrorrhizine |
Molecular Formula | C20H20NO4 |
Molecular Weight | 338.38 |
Solubility | Soluble in DMSO |
Purity | HPLC≥98% |
Appearance | Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 222-817-3 |
MDL | MFCD01310242 |
SMILES | COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1 |
Target Point | AChE |
Passage | Neuronal Signaling |
Background | Jatrorrhizine is an inhibitor of uptake-2 transporter. |
Biological Activity | Jatrorrhizine 是一种有效的口服活性 uptake-2 transporter 抑制剂,可以从各种中药植物中分离出来。 Jatrorrhizine 通过抑制 HT22 海马神经元中的 MAPK 途径,在 H2O2 诱导的细胞凋亡中发挥关键的神经保护作用[1]。 |
Data Literature Source | [1]. Sun S, et al. Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice. Xenobiotica. 2019 Oct; 49 (10) :1237-1243 |
Unit | Bottle |
Specification | 5mg 10mg 20mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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