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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > LycopeneCAS：502-65-8
Molecular Formula：C40H56
Molecular Weight：536.87
Storage：Powder:-20℃，1 year
Purity：HPLC≥90%
Appearance：Red to reddish brown Solid
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| CAS | 502-65-8 |
| Name | Lycopene |
| Molecular Formula | C40H56 |
| Molecular Weight | 536.87 |
| Solubility | Soluble in Chloroform ≥1mg/mL(The product is easily oxidized, so it is recommended to use it now) |
| Purity | HPLC≥90% |
| Appearance | Red to reddish brown Solid |
| Storage | Powder:-20℃，1 year |
| EC | EINECS 207-949-1 |
| MDL | MFCD00017350 |
| SMILES | C/C(C)=C\CC/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(/C=C/C=C(C)/C=C/C=C(CC/C=C(C)\C)\C)C |
| Target Point | Reactive oxygen species (ROS) |
| Passage | Immunology & Inflammation |
| Background | It is a carotenoid. The long-chain polyunsaturated olefin molecular structure has strong ability to eliminate free radicals and anti-oxidation. |
| Biological Activity | Lycopene是番茄，番茄产品和其他红色水果和蔬菜中天然存在的类胡萝卜素; 具有抗氧化作用。[1-5] |
| Data Literature Source | [1]. Assar EA， et al. Lycopene acts through inhibition of IκB kinase to suppress NF-κB signaling in human prostate and breast cancer cells. Tumour Biol. 2016 Jul; 37 (7) :9375-85. [2]. Tapiero H， et al. The role of carotenoids in the prevention of human pathologies. Biomed Pharmacother. 2004 Mar; 58 (2) :100-10. [3]. Müller L， et al. Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases-A Critical Review. Crit Rev Food Sci Nutr. 2016 Aug 17; 56 (11) :1868-79. [4]. Abass MA， et al. Lycopene ameliorates atrazine-induced oxidative damage in adrenal cortex of male rats by activation of the Nrf2/HO-1 pathway. Environ Sci Pollut Res Int. 2016 Aug; 23 (15) :15262-74. [5]. Bandeira AC， et al. Lycopene inhibits reactive oxygen species production in SK-Hep-1 cells and attenuates acetaminophen-induced liver injury in C57BL/6 mice. Chem Biol Interact. 2017 Feb 1; 263:7-17. |
| Unit | Bottle |
| Specification | 10mg 20mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Li X, et al. Drug Des Devel Ther. 2019 Jul 11;132331-2342
Li X, et al. Drug Des Devel Ther. 2019 Jul 11;132331-2342
Li X, et al. Drug Des Devel Ther. 2019 Jul 11;132331-2342
Xu XD, et al. Biochem Biophys Res Commun. 2020 Jun 4;526(3)699-705.
Li X, et al. Drug Des Devel Ther. 2019 Jul 11;132331-2342.
Xu XD, et al. Biochem Biophys Res Commun. 2020 Jun 4;526(3)699-705.
Xu XD, et al. Biochem Biophys Res Commun. 2020 Jun 4;526(3)699-705.
Sorry, there is no more information.
Lycopene protects against myocardial ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening
Click to check >>Author：Li X; Jia P; Huang Z; Liu S; Miao J; Guo Y; Wu N;
IF：3.3490
Publish_to：Drug Des Devel Ther
PMID：31371925
Effects of lycopene on vascular remodeling through the LXR-PI3K-AKT signaling pathway in APP/PS1 mice
Click to check >>Author：Xu XD; Teng Y; Zou JY; Ye Y; Song H; Wang ZY
IF：3.3070
Publish_to：Biochem Biophys Res Commun
PMID：32253029
Protective effects of lycopene against AFB1-induced erythrocyte dysfunction and oxidative stress in mice
Click to check >>Author：Zhang J; Wang P; Xu F; Huang W; Ji Q; Han Y; Shao
IF：2.3720
Publish_to：Res Vet Sci
PMID：31954314
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