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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > NeferineCAS：2292-16-2
Molecular Formula：C38H44N2O6
Molecular Weight：624.77
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 2292-16-2 |
| Name | Neferine |
| Molecular Formula | C38H44N2O6 |
| Molecular Weight | 624.77 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01707128 |
| SMILES | OC1=CC=C(C[C@@H]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC5=C(C=C4OC)CCN(C)[C@@H]5CC6=CC=C(OC)C=C6 |
| Target Point | NF-kB |
| Passage | NF-κB |
| Background | Neferine, a bisbenzylisoquinoline alkaloid, potently inhibits NF-κB activation. |
| Biological Activity | Neferine 是一种双苄基异喹啉类生物碱。Neferine 强效抑制 NF-κB 激活。 |
| Data Literature Source | [1]. Baskaran R，et al. Neferine prevents NF-κB translocation and protects muscle cells from oxidative stress and apoptosis induced by hypoxia. Biofactors. 2016 Jul 8;42(4):407-17. [2]. Liu X，et al. Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice. Oncotarget. 2016 Sep 20;7(38):61703-61715. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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