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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > Naringin dihydrochalconeCAS：18916-17-1
Molecular Formula：C27H34O14
Molecular Weight：582.55
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 18916-17-1 |
| Name | Naringin dihydrochalcone |
| Molecular Formula | C27H34O14 |
| Molecular Weight | 582.55 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD08436145 |
| SMILES | O=C(C1=C(O)C=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O[C@@]3([H])[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)C=C1O)CCC4=CC=C(O)C=C4 |
| Target Point | NF-kB |
| Passage | NF-κB |
| Background | Naringin Dihydrochalcone is a sweetener derived from naringin. |
| Biological Activity | 柚皮素表现出抗氧化，抗炎和抗细胞凋亡等生物活性。Naringin 可抑制 NF-κB 信号通路。[1-4] |
| Data Literature Source | [1]. Chen F， et al. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction. PLoS One. 2015 Nov 30; 10 (11) :e0143868. [2]. Raha S， et al. Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells. Int J Oncol. 2015 Sep; 47 (3) :1061-9. [3]. Kulasekaran G， et al. Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells. Mol Cell Biochem. 2015 Nov; 409 (1-2) :199-211. [4]. Wang D， et al. Naringin Improves Neuronal Insulin Signaling， Brain Mitochondrial Function， and Cognitive Function in High-Fat Diet-Induced Obese Mice. Cell Mol Neurobiol. 2015 Oct; 35 (7) :1061-71 |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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