Polydatin
Cat.No:IP0770 Solarbio
CAS:27208-80-6
Molecular Formula:C20H22O8
Molecular Weight:390.38
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
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Size:
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ER Stress >
PolydatinCAS:27208-80-6
Molecular Formula:C20H22O8
Molecular Weight:390.38
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 27208-80-6 |
Name | Polydatin |
Molecular Formula | C20H22O8 |
Molecular Weight | 390.38 |
Solubility | Soluble in DMSO ≥78mg/mL |
Purity | HPLC≥98% |
Appearance | White to off-white Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD00210592 |
SMILES | O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC(/C=C/C3=CC=C(O)C=C3)=CC(O)=C2.[(E)] |
Target Point | ER Stress |
Passage | ER Stress |
Background | Polydatin exists in the roots of Polygonum cuspidatum, a traditional Chinese medicine, and has anti-inflammatory activity. Polydatin has been reported to inhibit G6PD and induce oxidation and endoplasmic reticulum stress. |
Biological Activity | Polydatin提取自从传统中药虎杖根,在多个实验模型中具有抗炎作用。[1-3] |
Data Literature Source | [1]. Cheng Y,et al. Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia-reperfusioninjury. Brain Res. 2006 Sep 19;1110(1):193-200. [2]. Wang HL,et al. Synergistic effects of Polydatin and Vitamin C in Inhibiting Cardiotoxicity induced by Doxorubicin in rats. Fundam Clin Pharmacol. 2016 Nov 28. [Epub ahead of print] [3]. Jiang KF,et al. Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway. Acta Pharmacol Sin. 2016 Nov 28. [Epub ahead of print] |
Unit | Bottle |
Specification | 100mg 10mM*1mL in DMSO 500mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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