Didymin
Cat.No:ID0810 Solarbio
CAS:14259-47-3
Molecular Formula:C28H34O14
Molecular Weight:594.56
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Apoptosis >
DidyminCAS:14259-47-3
Molecular Formula:C28H34O14
Molecular Weight:594.56
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 14259-47-3 |
Name | Didymin |
Molecular Formula | C28H34O14 |
Molecular Weight | 594.56 |
Solubility | Soluble in DMSO |
Purity | HPLC≥98% |
Appearance | White to off-white Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 238-139-6 |
MDL | MFCD00151177 |
SMILES | O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)O4)O)O)O)=CC(O)=C13 |
Target Point | Apoptosis;N-Myc |
Passage | Apoptosis |
Background | Didymin is a flavonoid glycoside with antioxidant activity. It induces apoptosis by inhibiting N-Myc and up-regulating RKIP. |
Biological Activity | Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma[1]. |
Data Literature Source | [1]. Singhal J,Nagaprashantha LD,Vatsyayan R,Ashutosh,Awasthi S,Singhal SS. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. Cancer Prev Res (Phila). 2012 Mar;5(3):473-83. |
Unit | Piece |
Specification | 5mg 10mM*1mL in DMSO 10mg 20mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.
Click to check >>Author:Gu L; Sun M; Li R; Zhang X; Tao Y; Yuan Y; Luo X;
IF:6.7560
Publish_to:Front Immunol.
PMID:35154128