{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > TriiodothyronineCAS：6893/2/3
Molecular Formula：C15H12I3NO4
Molecular Weight：650.97
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to brown Solid
Qty：
Size：
| CAS | 6893/2/3 |
| Name | Triiodothyronine |
| Molecular Formula | C15H12I3NO4 |
| Molecular Weight | 650.97 |
| Solubility | Soluble in DMSO ≥10mg/mL，Soluble in Ethanol < 1mg/mL；Soluble in Water< 3mg/mL |
| Purity | ≥98% |
| Appearance | White to brown Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 229-999-3 |
| MDL | MFCD00002593 |
| SMILES | OC1=C(I)C=C(OC2=C(I)C=C(C[C@H](N)C(O)=O)C=C2I)C=C1 |
| InChIKey | AUYYCJSJGJYCDS-LBPRGKRZSA-N |
| InChI | InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1 |
| PubChem CID | 5920 |
| Target Point | Thyroid Hormone Receptor |
| Passage | Endocrinology & Hormones |
| Background | It is a potent agonist of thyroid hormone receptors TRα and TRβ. |
| Biological Activity | 3,3',5-Triiodo-L-thyronine是有效的甲状腺激素受体 TRα 和 TRβ 的激动剂，Ki 值为2.3 nM。[1-2] |
| Data Literature Source | [1]. Lin KH， et al. Stimulation of proliferation by 3，3'，5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14; 85 (2) :189-94. [2]. Bhat MK， et al. Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3，3'，5-triiodo-L-thyronine. Biochem Biophys Res Commun. 1993 Aug 31; 195 (1) :385-92. |
| Unit | Piece |
| Specification | 50mg 10mM*1mL in DMSO 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
