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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > SaracatinibCAS：379231-04-6
Molecular Formula：C27H32ClN5O5
Molecular Weight：542.03
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to yellow Solid
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| CAS | 379231-04-6 |
| Name | Saracatinib |
| Molecular Formula | C27H32ClN5O5 |
| Molecular Weight | 542.03 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 1592732-453-0 |
| MDL | MFCD09832698 |
| SMILES | ClC1=CC=C2C(OCO2)=C1NC3=C4C(OC5CCOCC5)=CC(OCCN6CCN(C)CC6)=CC4=NC=N3 |
| Target Point | Src |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | Saracatinib is a potent Src inhibitor. |
| Biological Activity | Saracatinib（AZD0530）是一种Src抑制剂，在体外表现出有效的抗迁移和抗侵袭作用，并抑制膀胱癌小鼠模型的转移。[1-2] |
| Data Literature Source | [1]. Green TP，et al. Preclinical anticancer activity of the potent，oral Src inhibitor AZD0530. Mol Oncol，2009，3(3)，248-261. [2]. Fuse MA，et al. Combination Therapy With c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells. Mol Cancer Ther. Mol Cancer Ther. 2017 Nov;16(11):2387-2398. |
| Unit | Bottle |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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