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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > CP-724714CAS：537705-08-1
Molecular Formula：C27H27N5O3
Molecular Weight：469.53
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 537705-08-1 |
| Name | CP-724714 |
| Molecular Formula | C27H27N5O3 |
| Molecular Weight | 469.53 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C(OCC)NC/C=C/C1=CC2=C(NC3=CC=C(OC4=CC=C(C)N=C4)C(C)=C3)N=CN=C2C=C1 |
| Target Point | HER2 inhibitor |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | CP-724714 is a potent and selective ErbB2 (HER2) tyrosine kinase inhibitor. |
| Biological Activity | CP-724714是一种有效的，选择性HER2/ErbB2抑制剂，IC50为10 nM，无细胞试验中比作用于EGFR，InsR，IRG-1R，PDGFR，VEGFR2，Abl，Src，c-Met等选择性高640多倍。[1] |
| Data Literature Source | [1] Jani JP，et al. Cancer Res，2007，67(20)，9887-9893. [2] Feng B，et al. Toxicol Sci，2009，108(2)，492-500. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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