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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Cinacalcet HydrochlorideCAS：364782-34-3
Molecular Formula：C22H23ClF3N
Molecular Weight：393.88
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥99%
Appearance：White to off-white Solid
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| CAS | 364782-34-3 |
| Name | Cinacalcet Hydrochloride |
| Molecular Formula | C22H23ClF3N |
| Molecular Weight | 393.88 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥99% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 620-490-5 |
| MDL | MFCD08067750 |
| SMILES | FC(F)(C1=CC(CCCN[C@@H](C2=C3C=CC=CC3=CC=C2)C)=CC=C1)F.Cl |
| Target Point | CaSR (calcium-sensing receptor) |
| Passage | GPCR & G Protein |
| Background | Cinacalcet hydrochloride is a Ca receptor (CaR) agonist. |
| Biological Activity | Cinacalcet hydrochloride 是一种可口服的 Ca receptor (CaR) 激动剂，用于治疗心血管疾病。[1-2] |
| Data Literature Source | [1]. Colloton M，et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67(2):467-76. [2]. D.A. Bushinsky，et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92 |
| Unit | Bottle |
| Specification | 10mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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