{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > PHT 427CAS：1191951-57-1
Molecular Formula：C20H31N3O2S2
Molecular Weight：409.61
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥99%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1191951-57-1 |
| Name | PHT 427 |
| Molecular Formula | C20H31N3O2S2 |
| Molecular Weight | 409.61 |
| Solubility | Soluble in DMSO |
| Purity | ≥99% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD18384970 |
| SMILES | CCCCCCCCCCCCC1=CC=C(C=C1)S(NC2=NN=CS2)(=O)=O |
| Target Point | Akt;PDK1 |
| Passage | PI3K/Akt/mTOR |
| Background | PHT-427 is a dual inhibitor of Akt and PDPK1. |
| Biological Activity | PHT-427 是一种 Akt 和 PDPK1 双重抑制剂，与 Akt 和 PDPK1 中的 PH 结构域有亲和性，Ki 分别为 2.7 μM 和 5.2 μM。[1] |
| Data Literature Source | [1]. Meuillet EJ，et al. Molecular pharmacology and antitumor activity of PHT-427，a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17 |
| Unit | Bottle |
| Specification | 10mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
