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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > CilomilastCAS：153259-65-5
Molecular Formula：C20H25NO4
Molecular Weight：343.42
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 153259-65-5 |
| Name | Cilomilast |
| Molecular Formula | C20H25NO4 |
| Molecular Weight | 343.42 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-258-5 |
| MDL | MFCD00924373 |
| SMILES | O=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O |
| Target Point | Phosphodiesterase (PDE) |
| Passage | Metabolic Enzyme&Protease |
| Background | Cilomilast/SB 207499/Ariflo is a PDE4 inhibitor. |
| Data Literature Source | [1]. Griswold DE，et，al. SB 207499 (Ariflo)，a second generation phosphodiesterase 4 inhibitor，reduces tumor necrosis factor alpha and interleukin-4 production in vivo. J Pharmacol Exp Ther. 1998 Nov;287(2):705-11. [2]. Barnette MS，et，al. SB 207499 (Ariflo)，a potent and selective second-generation phosphodiesterase 4 inhibitor: in vitro anti-inflammatory actions. J Pharmacol Exp Ther. 1998 Jan;284(1):420-6. |
| Unit | Bottle |
| Specification | 5mg 25mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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