Thiazovivin
Cat.No:IT1410 Solarbio
CAS:1226056-71-8
Molecular Formula:C15H13N5OS
Molecular Weight:311.36
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to brown Solid
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Cytoskeleton >
ThiazovivinCAS:1226056-71-8
Molecular Formula:C15H13N5OS
Molecular Weight:311.36
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to brown Solid
Qty:
Size:
CAS | 1226056-71-8 |
Name | Thiazovivin |
Molecular Formula | C15H13N5OS |
Molecular Weight | 311.36 |
Solubility | Soluble in DMSO |
Purity | ≥98% |
Appearance | White to brown Solid |
Storage | Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 808-340-9 |
MDL | MFCD16495823 |
SMILES | O=C(C1=CSC(NC2=NC=NC=C2)=N1)NCC3=CC=CC=C3 |
Target Point | ROCK |
Passage | Cytoskeleton; Cell Cycle;TGF-beta/Smad;Stem Cells |
Background | Thiazovivin is a potent ROCK inhibitor. |
Biological Activity | Thiazovivin 是一种有效的 ROCK 抑制剂,对人胚胎干细胞具有保护作用。[1-2] |
Data Literature Source | [1]. Xu Y,et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8129-34. [2]. Park S,et al. Thiazovivin,a Rho kinase inhibitor,improves stemness maintenance of embryo-derived stem-like cells under chemically defined culture conditions in cattle. Anim Reprod Sci. 2015 Oct;161:47-57 |
Unit | Bottle |
Specification | 5mg 10mg 50mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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