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Acefylline

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Cat.No：IA2050 Solarbio

CAS：652-37-9

Molecular Formula：C₉H₁₀N₄O₄

Molecular Weight：238.2

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	652-37-9
Name	Acefylline
Molecular Formula	C₉H₁₀N₄O₄
Molecular Weight	238.2
Solubility	Soluble in DMSO
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 211-490-2
MDL	MFCD00022832
SMILES	O=C(O)CN1C=NC(N(C)C(N2C)=O)=C1C2=O
Target Point	Adenosine Receptor
Passage	GPCR & G Protein
Background	It is an antagonist of adenosine receptors and an activator of peptidylarginine deiminase (PAD).
Biological Activity	Acefylline (Theophyllineacetic acid)， a xanthine derivative， is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator， which inhibits rat lung cAMP phosphodiesterase isoenzymes[1-2].
Data Literature Source	[1]. Ferretti C，et al. Inhibitory effect of theophylline，theophylline-7-acetic acid，ambroxol and ambroxol-theophylline-7-acetate on rat lung cAMP phosphodiesterase isoenzymes. Int J Tissue React. 1992;14(1):31-6. [2]. Méchin MC，et，al. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. J Dermatol Sci. 2016 Feb;81(2):101-6.
Unit	Bottle
Specification	100mg 200mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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