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My CartCAS：1192491-61-4
Molecular Formula：C7H10N3NaO6S
Molecular Weight：287.23
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 1192491-61-4 |
| Name | Avibactam sodium |
| Molecular Formula | C7H10N3NaO6S |
| Molecular Weight | 287.23 |
| Solubility | Soluble in Water/DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28900719 |
| SMILES | O=S(ON1[C@]2([H])CC[C@@H](C(N)=O)[N@@](C2)C1=O)([O-])=O.[Na+] |
| InChIKey | RTCIKUMODPANKX-JBUOLDKXSA-M |
| InChI | InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1 |
| PubChem CID | 24944097 |
| Target Point | β-lactamase |
| Passage | Anti-infection |
| Background | Avibactam sodium/NXL-104 is a reversible β-lactamase inhibitor |
| Biological Activity | Avibactam (AVE-1330A, NXL104) is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.Avibactam is a novel non-β-lactam β-lactamase inhibitor that inhibits a wide range of β-lactamases. [1-2] |
| Data Literature Source | [1] Zhanel GG，et al. Drugs. 2013，73(2):159-77. [2] Lahiri SD，et al. Antimicrob Agents Chemother. 2014，58(10):5 |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Rapid Identification of Carbapenemase-Producing Klebsiella pneumoniae Using Headspace Solid-Phase Microextraction Combined with Gas Chromatography-Mass Spectrometry
Click to check >>Author：Hong Luo, Yaping Hang, Hongying Zhu, Qiaoshi Zhong, Suqin Peng, Shumin Gu, Xueyao Fang, Longhua Hu
IF：4.1770
Publish_to：Infection and Drug Resistance
PMID：37152404
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