English Name |
Anti-PIM1 Polyclonal Antibody |
Chinese Name |
丝氨酸/苏氨酸激酶蛋白Pim1抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:1000-3000. |
Target |
PIM1 |
Synonyms |
Oncogene PIM 1, Oncogene PIM1, PIM 1, pim 1 kinase 44 kDa isoform, Pim 1 kinase, pim 1 oncogene (proviral integration site 1), Pim 1 oncogene, PIM, PIM1, pim1 kinase 44 kDa isoform, PIM1_HUMAN, Pim2, PIM3, Proto oncogene serine/threonine protein kinase Pim 1, Proto-oncogene serine/threonine-protein kinase Pim-1, Proviral integration site 1, Proviral integration site 2 |
Background |
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810). |
Swiss Prot |
P11309 |
Gene ID |
5292 |
Subcellular Location |
Nucleus Cytoplasm Cell membrane |
Immunogen |
A synthetic peptide of Human PIM1 |
Public Immunogen Range |
263-313/313aa |
Calculated MW |
36/45kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Y-Dilution Ratio |
WB 1:1000-3000. ELISA 1:1000-10000. |
Specification |
50ul 100ul |
Reactivity |
Human Rat Mouse |
Application |
WB ELISA |