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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > Carbidopa MonohydrateCAS：38821-49-7
Molecular Formula：C10H14N2O4·H2O
Molecular Weight：244.24
Storage：Powder:-20℃，2 years
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 38821-49-7 |
| Name | Carbidopa Monohydrate |
| Molecular Formula | C10H14N2O4·H2O |
| Molecular Weight | 244.24 |
| Solubility | Soluble in --- |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years |
| EC | EINECS 642-905-9 |
| MDL | MFCD00889211 |
| SMILES | OC1=C(O)C=CC(C[C@](C)(NN)C(O)=O)=C1.O |
| InChIKey | QTAOMKOIBXZKND-PPHPATTJSA-N |
| InChI | InChI=1S/C10H14N2O4.H2O/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4,12-14H,5,11H2,1H3,(H,15,16);1H2/t10-;/m0./s1 |
| PubChem CID | 38101 |
| Target Point | Decarboxylase inhibitor |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a peripheral decarboxylase inhibitor and selective aryl hydrocarbon receptor (AhR) modulator. |
| Biological Activity | S-(-)-Carbidopa是一种外周型脱羧酶 (decarboxylase) 抑制剂，可用于帕金森病的研究。S-(-)-Carbidopa是一种选择性AhR调节剂。S-(-)-Carbidopa抑制胰腺癌细胞和肿瘤生长[1-3]。 |
| Data Literature Source | [1]. Safe S. Carbidopa: a selective Ah receptor modulator (SAhRM). Biochem J. 2017;474(22):3763-3765. Published 2017 Nov 6. [2]. Fermaglich J. Treatment of Parkinson's disease with carbidopa，a peripheral decarboxylase inhibitor，and levodopa. Med Ann Dist Columbia. 1974;43(12):587-591. [3]. Gilbert JA，et al. The aromatic-L-amino acid decarboxylase inhibitor carbidopa is selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells. Clin Cancer Res. 2000;6(11):4365-4372. |
| Unit | Bottle |
| Specification | 20mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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