{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > ChloroheminCAS：16009-13-5
Molecular Formula：C34H32ClFeN4O4
Molecular Weight：651.94
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Blue-black Solid
Qty：
Size：
| CAS | 16009-13-5 |
| Name | Chlorohemin |
| Molecular Formula | C34H32ClFeN4O4 |
| Molecular Weight | 651.94 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | Blue-black Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 240-140-1 |
| MDL | MFCD00010726 |
| SMILES | [Cl-][Fe+3]123[N-]4C5=C(CCC([O-])=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC([O-])=O)=[N]3C8=C5.[H+].[H+] |
| Target Point | Heme oxygenase;HO-1 |
| Passage | Metabolic Enzyme&Protease |
| Background | Chlorohemin is an iron containing porphyrin compound and an inducer of Heme oxygenase (HO) -1. |
| Biological Activity | Hemin 是含铁的卟啉化合物。Hemin 是血红素加氧酶 (HO)-1 诱导剂。[1-2] |
| Data Literature Source | [1]. Vanova K， et al. Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells. BMC Cancer. 2016 May 12; 16:309. [2]. Chen HH， et al. Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation. Biochim Biophys Acta. 2015 Oct; 1852 (10 Pt A) :2195-201 |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Gao Z, Li Z, Li X, Xiao J, Li C. Front Cell Dev Biol. 2023 Jun 1;11:1161541.
Sorry, there is no more information.
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance; neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis
Click to check >>Author：Cheng X; Chi L; Lin T; Liang F; Pei Z; Sun J; Teng
IF：9.3000
Publish_to：J Neuroinflammation
PMID：36864466
Enhancing cell adhesive and antibacterial activities of glass-fibre-reinforced polyetherketoneketone through Mg & Ag PIII
Click to check >>Author：Tan Xin, Wang Zhongyi, Yang Xin, Yu Ping, Sun Manlin, Zhao Yuwei, Yu Haiyang
IF：6.7000
Publish_to：Regenerative Biomaterials
PMID：37489146
ATGL-mediated lipophagy balances cholesterol-induced inflammation in pathogen infected Apostichopus japonicus coelomocytes
Click to check >>Author：Yuan Su, Zilian Jiang, Yahui Wang, Hongfang Zhang
IF：6.2000
Publish_to：ANALYTICA CHIMICA ACTA
PMID：37355338
CircLphn3 protects the blood-brain barrier in traumatic brain injury
Click to check >>Author：Cheng YQ; Wu CR; Du MR; Zhou Q; Wu BY; Fu JY; Bala
IF：6.1000
Publish_to：Neural Regen Res
PMID：34472480
Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions
Click to check >>Author：Gao Z; Li Z; Li X; Xiao J; Li C
IF：5.5000
Publish_to：Front Cell Dev Biol
PMID：37325570
A drug-loaded composite coating to improve osteogenic and antibacterial properties of Zn–1Mg porous scaffolds as biodegradable bone implants
Click to check >>Author：Huang Yina, Zhang Lu, Tan Lingping, Zhang Chi, Li Xiting, Wang Panpan, Gao Li, Zhao Chuanjiang
IF：5.1000
Publish_to：INFLAMMATION
PMID：37310646
Manual Download
