Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > (-)-Blebbistatin

(-)-Blebbistatin

Manual Download

Cat.No：IB0610 Solarbio

CAS：856925-71-8

Molecular Formula：C₁₈H₁₆N₂O₂

Molecular Weight：292.33

Storage：Powder:-20℃,2 years

Purity：≥98%

Appearance：Light yellow to yellow Solid

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	856925-71-8
Name	(-)-Blebbistatin
Molecular Formula	C₁₈H₁₆N₂O₂
Molecular Weight	292.33
Solubility	Soluble in DMSO(This product is not stable in solution, it is recommended that you use it now)
Purity	≥98%
Appearance	Light yellow to yellow Solid
Storage	Powder:-20℃,2 years
MDL	MFCD08460907
SMILES	CC1=CC=C(N=C(N(C2=CC=CC=C2)CC3)[C@]3(O)C4=O)C4=C1
InChIKey	LZAXPYOBKSJSEX-GOSISDBHSA-N
InChI	InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m1/s1
PubChem CID	5287792
Target Point	Myosin
Passage	Cytoskeleton
Background	Blebbistatin is a potent and selective myosin II inhibitor.
Biological Activity	(-)-Blebbistatin是布雷他汀的S对映体。 Blebbistatin是有效且选择性的 myosin II 抑制剂，IC50 范围为0.5至5 μM。[1-3]
Data Literature Source	[1]. Limouze J，et al. Specificity of blebbistatin，an inhibitor of myosin II. J Muscle Res Cell Motil. 2004;25(4-5):337-41. [2]. Kovács M，et al. Mechanism of blebbistatin inhibition of myosin II. J Biol Chem. 2004 Aug 20;279(34):35557-63. [3]. Liu Z，et al. Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells. Br J Pharmacol. 2010 Jan 1;159(2):304-15. [4]. Zhang X，et al. In vitro and in vivo relaxation of urinary bladder smooth muscle by the selective myosin IIinhibitor，blebbistatin. BJU Int. 2011 Jan;107(2):310-7.
Unit	Piece
Specification	5mg 10mg 25mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.