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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > BAM7CAS：331244-89-4
Molecular Formula：C21H19N5O2S
Molecular Weight：405.47
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 331244-89-4 |
| Name | BAM7 |
| Molecular Formula | C21H19N5O2S |
| Molecular Weight | 405.47 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01246556 |
| SMILES | CCOC1=CC=CC=C1N/N=C2C(C)=NN(C3=NC(C4=CC=CC=C4)=CS3)C\2=O |
| InChIKey | WRLVHADVOGFZOZ-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H19N5O2S/c1-3-28-18-12-8-7-11-16(18)23-24-19-14(2)25-26(20(19)27)21-22-17(13-29-21)15-9-5-4-6-10-15/h4-13,25H,3H2,1-2H3 |
| PubChem CID | 3101542 |
| Target Point | Bcl-2 Family;BAX |
| Passage | Apoptosis |
| Background | BAM7 is a direct and selective BAX activator. |
| Biological Activity | BAM7 是一种直接的选择性 BAX 激活剂，IC50 为 3.3 μM[1]。 |
| IC50 | Bax:3.3μM [1] |
| Data Literature Source | [1]. Gavathiotis E，et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat Chem Biol. 2012 Jul;8(7):639-45 |
| Unit | Piece |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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