Ferrostatin-1
Cat.No:IF0430 Solarbio
CAS:347174-05-4
Molecular Formula:C15H22N2O2
Molecular Weight:262.35
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Solid
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Apoptosis >
Ferrostatin-1CAS:347174-05-4
Molecular Formula:C15H22N2O2
Molecular Weight:262.35
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Solid
Qty:
Size:
CAS | 347174-05-4 |
Name | Ferrostatin-1 |
Molecular Formula | C15H22N2O2 |
Molecular Weight | 262.35 |
Solubility | Soluble in DMSO |
Purity | ≥98% |
Appearance | Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD08072959 |
SMILES | O=C(OCC)C1=CC=C(NC2CCCCC2)C(N)=C1 |
InChIKey | UJHBVMHOBZBWMX-UHFFFAOYSA-N |
InChI | InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3 |
PubChem CID | 4068248 |
Target Point | Ferroptosis |
Passage | Apoptosis |
Background | Ferrostatin-1 is a potent inhibitor of ferroptosis. |
Biological Activity | Ferrostatin-1 是Ferroptosis 的强效抑制剂,其 EC50 值为 60 nM[1]。 |
IC50 | EC50: 60nM(Ferroptosis)[1] |
Data Literature Source | [1]. Dixon SJ,et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012 May 25;149(5):1060-72. [2]. Kabiraj P,et al. The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells. Protein J. 2015 Oct;34(5):349-58. |
Unit | Piece |
Specification | 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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