{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > FruquintinibCAS：1194506-26-7
Molecular Formula：C21H19N3O5
Molecular Weight：393.39
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1194506-26-7 |
| Name | Fruquintinib |
| Molecular Formula | C21H19N3O5 |
| Molecular Weight | 393.39 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00001293 |
| SMILES | O=C(C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12)NC |
| InChIKey | BALLNEJQLSTPIO-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H19N3O5/c1-11-19(20(25)22-2)13-6-5-12(7-16(13)28-11)29-21-14-8-17(26-3)18(27-4)9-15(14)23-10-24-21/h5-10H,1-4H3,(H,22,25) |
| PubChem CID | 44480399 |
| Target Point | VEGFR3，VEGFR1，VEGFR2 |
| Passage | Angiogenesis;Protein Tyrosine Kinase/RTK |
| Background | Fruquintinib is a potent and selective VEGFR 1/2/3 inhibitor. |
| Biological Activity | Fruquintinib是有效，选择性的 VEGFR 1/2/3 抑制剂，IC50 值分别为33，0.5，and 35 nM[1]。 |
| IC50 | VEGFR1:33nM;VEGFR2:35nM;VEGFR3:0.5nM [1] |
| Data Literature Source | [1]. Sun Q，et al. Discovery of fruquintinib，a potent and highly selective small molecule inhibitor of VEGFR 1，2，3 tyrosine kinases for cancer therapy. Cancer Biol Ther. 2014;15(12):1635-45. |
| Unit | Piece |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
