{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > FulvestrantCAS：129453-61-8
Molecular Formula：C32H47F5O3S
Molecular Weight：606.77
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 129453-61-8 |
| Name | Fulvestrant |
| Molecular Formula | C32H47F5O3S |
| Molecular Weight | 606.77 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 642-998-6 |
| MDL | MFCD00903953 |
| SMILES | C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2 |
| InChIKey | VWUXBMIQPBEWFH-WCCTWKNTSA-N |
| InChI | InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1 |
| PubChem CID | 104741 |
| Target Point | Estrogen Receptor/ERR |
| Passage | Endocrinology & Hormones |
| Background | Fulvestrant is a potent estrogen receptor (Estrogen Receptor) antagonist. |
| Biological Activity | Fulvestrant是有效的雌激素受体 (Estrogen Receptor) 拮抗剂，IC50值为 9.4 nM。[1-3] |
| IC50 | 9.4nM(Estrogen Receptor)[1] |
| Data Literature Source | [1]. Wakeling AE，et al. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991 Aug 1;51(15):3867-73. [2]. Osborne CK，et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6. [3]. Garner F，et al. RAD1901: a novel，orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56 |
| Unit | Piece |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
