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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > KN 93CAS：139298-40-1
Molecular Formula：C26H29ClN2O4S
Molecular Weight：501.04
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 139298-40-1 |
| Name | KN 93 |
| Molecular Formula | C26H29ClN2O4S |
| Molecular Weight | 501.04 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00236424 |
| SMILES | O=S(C1=CC=C(OC)C=C1)(N(C2=CC=CC=C2CN(C/C=C/C3=CC=C(Cl)C=C3)C)CCO)=O |
| InChIKey | LLLQTDSSHZREGW-AATRIKPKSA-N |
| InChI | InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+ |
| PubChem CID | 5312122 |
| Target Point | CaMK |
| Passage | Neuronal Signaling |
| Background | KN-93 is a cell-permeable and competitive reversible inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II). |
| Unit | Piece |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Costunolide covalently targets and inhibits CaMKII phosphorylation to reduce ischemia-associated brain damage
Click to check >>Author：Wenjuan Liu, Wei Yang, Ruixue Niu, Longfei Cong, Min Jiang, Gang Bai
IF：6.6560
Publish_to：PHYTOMEDICINE
PMID：37087789
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