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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > Liproxstatin-1CAS：950455-15-9
Molecular Formula：C19H21ClN4
Molecular Weight：340.85
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 950455-15-9 |
| Name | Liproxstatin-1 |
| Molecular Formula | C19H21ClN4 |
| Molecular Weight | 340.85 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00023421 |
| SMILES | ClC1=CC(CNC2=NC3=CC=CC=C3NC24CCNCC4)=CC=C1 |
| InChIKey | YAFQFNOUYXZVPZ-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H21ClN4/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18/h1-7,12,21,24H,8-11,13H2,(H,22,23) |
| PubChem CID | 135735917 |
| Target Point | Ferroptosis |
| Passage | Apoptosis |
| Background | Liproxstatin-1 is a potent ferroptosis inhibitor. |
| Biological Activity | Liproxstatin-1 是一种有效的 ferroptosis 抑制剂，IC50 值约为 38 nM。[1-2] |
| Data Literature Source | [1]. Friedmann Angeli JP，et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014 Dec;16(12):1180-91. [2]. Zilka O，et al. On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death. ACS Cent Sci. 2017 Mar 22;3(3):232-243 |
| Unit | Piece |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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