Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > MK-3207 Hydrochloride

MK-3207 Hydrochloride

Manual Download

Cat.No：IM1010 Solarbio

CAS：957116-20-0

Molecular Formula：C₃₁H₂₉F₂N₅O₃·HCl

Molecular Weight：594.05

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：Solid

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	957116-20-0
Name	MK-3207 Hydrochloride
Molecular Formula	C₃₁H₂₉F₂N₅O₃·HCl
Molecular Weight	594.05
Solubility	Soluble in DMSO ≥10mg/mL
Purity	≥98%
Appearance	Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 200-258-5
MDL	MFCD16038934
SMILES	O=C1C2(NC[C@@H](C3=CC(F)=CC(F)=C3)N1CC(NC4=CC5=C(C[C@@]6(C(NC7=C6C=CC=N7)=O)C5)C=C4)=O)CCCC2.Cl
InChIKey	VWKNXYACOMQRBX-KZCKSIIFSA-N
InChI	InChI=1S/C31H29F2N5O3.ClH/c32-21-10-19(11-22(33)13-21)25-16-35-31(7-1-2-8-31)29(41)38(25)17-26(39)36-23-6-5-18-14-30(15-20(18)12-23)24-4-3-9-34-27(24)37-28(30)40;/h3-6,9-13,25,35H,1-2,7-8,14-17H2,(H,36,39)(H,34,37,40);1H/t25-,30+;/m0./s1
PubChem CID	49867927
Target Point	CGRP Receptor
Passage	GPCR & G Protein;Neuronal Signaling
Background	MK-3207 Hydrochloride is a potent CGRP receptor antagonist.
Biological Activity	MK-3207 Hydrochloride 是一种有效的，可口服的 CGRP receptor 拮抗剂，IC50 值为 0.12 nM，Ki 值为 0.024 nM。[1]
IC50	0.12nM(CGRP receptor)[1]
Data Literature Source	[1]. Salvatore CA，et al. Pharmacological properties of MK-3207，a potent and orally active calcitonin gene-related peptide receptor antagonist. J Pharmacol Exp Ther. 2010 Apr;333(1):152-60.
Unit	Piece
Specification	5mg 10mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.