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L-Thyroxine

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Cat.No：IT0210 Solarbio

CAS：51-48-9

Molecular Formula：C₁₅H₁₁I₄NO₄

Molecular Weight：776.87

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to yellow Solid

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Product Information

CAS	51-48-9
Name	L-Thyroxine
Molecular Formula	C₁₅H₁₁I₄NO₄
Molecular Weight	776.87
Solubility	Soluble in DMSO ≥10mg/mL
Purity	≥98%
Appearance	White to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 200-101-1
MDL	MFCD00002595
SMILES	N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O)=O
InChIKey	XUIIKFGFIJCVMT-LBPRGKRZSA-N
InChI	InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
PubChem CID	5819
Target Point	Thyroid Hormone Receptor
Passage	Endocrinology & Hormones
Background	L-Thyroxine is a thyroid hormone that can be used in the study of hypothyroidism.
Biological Activity	L-Thyroxine (Levothyroxine; T4) 是一种合成的甲状腺激素，用于治疗甲状腺功能减退症。DIO 酶将 L-Thyroxine (T4) 转化成具有生物活性的三碘甲状腺氨酸 (T3)。[1-2]
Data Literature Source	[1]. Arici M，et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Jan 11. [2]. Corriveau S，et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2(4):144-149
Unit	Piece
Specification	100mg 10mM*1mL in DMSO 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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