English Name |
Anti-HTR2A Polyclonal Antibody |
Chinese Name |
5-羟色胺受体2A抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:1000-3000. IF 1:50-200. |
Target |
HTR2A |
Synonyms |
5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor, Serotonin receptor 2A, 5-HT-2A, 5-HT-2, HTR2A, Htr2a, 5 HT 2, 5HTR2A, 5 HT 2A, 5 HT2 receptor, 5 HT2A, 5 hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, 5-hydroxytryptamine 2A receptor, 5-hydroxytryptamine receptor 2A, 5HT2A_HUMAN, HTR 2, HTR 2A, HTR2, HTR2A |
Background |
G-protein coupled receptor for 5-hydroxytryptamine. Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. |
Swiss Prot |
P28223 |
Gene ID |
3356 |
Subcellular Location |
Cytoplasm |
Immunogen |
A synthetic peptide of Human HTR2A |
Public Immunogen Range |
421-471/471aa |
Calculated MW |
44/53kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Y-Dilution Ratio |
WB 1:1000-3000. IF 1:50-200. ELISA 1:2000-20000. |
Specification |
50ul 100ul |
Reactivity |
Human |
Application |
IF WB;IF WB ELISA |