English Name |
Anti-CD68 Polyclonal Antibody |
Chinese Name |
CD68抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-1000. IF 1:50-200. |
Target |
CD68 |
Synonyms |
CD 68, CD68 antigen, CD68 molecule, DKFZp686M18236, GP110, Macrophage antigen CD68 (microsialin), macrosialin, SCARD1, Scavenger receptor class D member 1, macrosialin isoform A precursor, CD68_HUMAN, Macrosialin, Gp110, scavenger receptor class D, member 1, macrophage antigen CD68, LAMP4 |
Background |
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. |
Swiss Prot |
P34810 |
Gene ID |
968 |
Subcellular Location |
Cell membrane Endosome membrane Lysosome membrane Single-pass type I membrane protein Single-pass type I membrane protein |
Immunogen |
A synthetic peptide of human CD68 |
Public Immunogen Range |
100-200aa |
Calculated MW |
31/34/37kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.03% Proclin300,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Piece |
Piece |
Specification |
50ul 100ul |
Reactivity |
Human Rat Mouse |
Application |
IF WB |