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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > SSR128129ECAS：848318-25-2
Molecular Formula：C18H15N2NaO4
Molecular Weight：346.31
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 848318-25-2 |
| Name | SSR128129E |
| Molecular Formula | C18H15N2NaO4 |
| Molecular Weight | 346.31 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD25976751 |
| SMILES | O=C([O-])C1=CC(C(C2=C(C)C(OC)=C3C=CC=CN23)=O)=CC=C1N.[Na+] |
| Target Point | FGFR |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | SSR128129E is an FGFR allosteric modulator. |
| Biological Activity | SSR128129E 是口服可用的 FGFR 变构调节剂， 对FGFR1 的 IC50 值为1.9 μM。[1] |
| Data Literature Source | [1]. Bono F，et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23(4):477-88. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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