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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > PP1CAS：172889-26-8
Molecular Formula：C16H19N5
Molecular Weight：281.36
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 172889-26-8 |
| Name | PP1 |
| Molecular Formula | C16H19N5 |
| Molecular Weight | 281.36 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01076570 |
| SMILES | NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(C)C=C3)=NC=N1 |
| InChIKey | ZVPDNRVYHLRXLX-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19) |
| PubChem CID | 1400 |
| Target Point | Fyn;LCK |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | PP1 is a potent selective Src family inhibitor that inhibits Lck and Fyn. |
| Biological Activity | PP1 是一种有效的选择性 Src 家族抑制剂，抑制 Lck 和 Fyn，IC50 分别为 5 和 6 nM。[1] |
| IC50 | 5nM(Lck)，6nM(Fyn)，250nM(EGFR)，>50μM(JAK2)[1] |
| Data Literature Source | [1]. Hanke JH，et al. Discovery of a novel，potent，and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem. 1996 Jan 12;271(2):695-701. |
| Unit | Bottle |
| Specification | 10mg 20mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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