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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > AZD4547CAS：1035270-39-3
Molecular Formula：C26H33N5O3
Molecular Weight：463.57
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 1035270-39-3 |
| Name | AZD4547 |
| Molecular Formula | C26H33N5O3 |
| Molecular Weight | 463.57 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22580423 |
| SMILES | C[C@@H]1CN(C[C@@H](N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC |
| Target Point | FGFR |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | AZD4547 is a novel selective FGFR inhibitor. |
| Biological Activity | AZD4547 是一种有效的 FGFR 家族抑制剂，作用于 FGFR1，FGFR2，FGFR3 和 FGFR4，IC50 分别为 0.2 nM，2.5 nM，1.8 nM 和 165 nM。[1] |
| IC50 | FGFR1:0.2nM;FGFR2:2.5nM;FGFR3:1.8nM;FGFR4:165nM[1] |
| Data Literature Source | [1]. Gavine PR，et al. AZD4547: an orally bioavailable，potent，and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res，2012，72(8)，2045-2056 |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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