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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > Pifithrin-μCAS：64984-31-2
Molecular Formula：C8H7NO2S
Molecular Weight：181.21
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to brown Solid
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| CAS | 64984-31-2 |
| Name | Pifithrin-μ |
| Molecular Formula | C8H7NO2S |
| Molecular Weight | 181.21 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00181531 |
| SMILES | O=S(C#CC1=CC=CC=C1)(N)=O |
| Target Point | p53 |
| Passage | Apoptosis |
| Background | Pifithrin-μ is a p53 and HSP70 inhibitor with antitumor and neuroprotective activities. |
| Biological Activity | Pifithrin-μ 是一种 p53 和 HSP70 的抑制剂，具有抗肿瘤和神经保护作用。[1-3] |
| Data Literature Source | [1]. Strom E，et al. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nat Chem Biol. 2006 Sep;2(9):474-9. Epub 2006 Jul 23. [2]. Zhou Y，et al. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70. Oncol Rep. 2017 Jan;37(1):313-322. [3]. Glas M，et al. Neuroprotection with the P53-Inhibitor Pifithrin-μ after Cardiac Arrest in a Rodent Model. Shock. 2018 Feb;49(2):229-234. |
| Unit | Bottle |
| Specification | 10mg 20mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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