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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > APR-246CAS：5291-32-7
Molecular Formula：C10H17NO3
Molecular Weight：199.25
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 5291-32-7 |
| Name | APR-246 |
| Molecular Formula | C10H17NO3 |
| Molecular Weight | 199.25 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C1C(COC)(CO)N2CCC1CC2 |
| Target Point | p53 |
| Passage | Apoptosis |
| Background | APR-246 is a biologically active compound. |
| Biological Activity | Eprenetapopt (APR-246, PRIMA-1MET)是一种小分子有机化合物，可以恢复肿瘤抑制功能，主要靶向 突变型p53 ，在多种癌细胞类型中诱导细胞死亡。APR-246 可诱导凋亡和自噬。[1-2] |
| Data Literature Source | [1] Mohell N，et al. Cell Death Dis. 2015 Jun 18;6:e1794. [2] Zandi R，et al. Clin Cancer Res. 2011 May 1;17(9):2830-41. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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