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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > CID755673CAS：521937-07-5
Molecular Formula：C12H11NO3
Molecular Weight：217.22
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 521937-07-5 |
| Name | CID755673 |
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 604-604-1 |
| MDL | MFCD03828155 |
| SMILES | O=C1NCCCC2=C1OC3=CC=C(O)C=C32 |
| InChIKey | AACFPJSJOWQNBN-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15) |
| PubChem CID | 755673 |
| Target Point | PKD |
| Passage | Apoptosis |
| Background | CID755673 is a pan-PKD1/2/3 inhibitor with cellular activity. |
| Biological Activity | CID755673 is a potent PKD inhibitor with IC50s of 182 nM， 280 nM and 227 nM for PKD1， PKD2 and PKD3， respectively.[1-2] |
| Data Literature Source | [1]. Sharlow ER， et al. Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone. J Biol Chem. 2008 Nov 28;283(48):33516-26. [2]. Venardos K， et al. The PKD inhibitor CID755673 enhances cardiac function in diabetic db/db mice. PLoS One. 2015 Mar 23;10(3):e0120934. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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