A-1331852
Cat.No:IA2530 Solarbio
CAS:1430844-80-6
Molecular Formula:C38H38N6O3S
Molecular Weight:658.81
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to yellow Solid
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Apoptosis >
A-1331852CAS:1430844-80-6
Molecular Formula:C38H38N6O3S
Molecular Weight:658.81
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to yellow Solid
Qty:
Size:
CAS | 1430844-80-6 |
Name | A-1331852 |
Molecular Formula | C38H38N6O3S |
Molecular Weight | 658.81 |
Solubility | Soluble in DMSO |
Purity | ≥98% |
Appearance | White to yellow Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
SMILES | O=C(C1=NC(N2CC3=C(C=CC=C3C(NC4=NC5=CC=CC=C5S4)=O)CC2)=CC=C1C6=C(C)N(CC7(C8)CC9CC8CC(C9)C7)N=C6)O |
Target Point | Bcl-xL |
Passage | Apoptosis |
Background | A-1331852 is a potent and selective BCL-XL inhibitor. |
Biological Activity | A-1331852 is an orally available BCL-XL selective inhibitor with a Ki of less than 10 pM.[1] |
Data Literature Source | [1]. Leverson JD,et al. Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy. Sci Transl Med. 2015 Mar 18;7(279):279ra40. |
Unit | Bottle |
Specification | 5mg 10mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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