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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > COTI-2CAS：1039455-84-9
Molecular Formula：C19H22N6S
Molecular Weight：366.48
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 1039455-84-9 |
| Name | COTI-2 |
| Molecular Formula | C19H22N6S |
| Molecular Weight | 366.48 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 604-604-1 |
| MDL | MFCD28502211 |
| SMILES | S=C(N1CCN(C2=NC=CC=C2)CC1)N/N=C3CCCC4=C\3N=CC=C4 |
| Target Point | p53 |
| Passage | Apoptosis |
| Background | COTI-2 is a third-generation thiocarbazide, an activator of mutant p53. |
| Biological Activity | COTI-2是一种具有口服活性的第三代胺苯硫脲，是突变型p53的激活剂，具有潜在的抗肿瘤活性。[1] |
| Data Literature Source | [1] Vladimir J N Bykov，et al. Nature Reviews Cancer. 2017. [2] Kowthar Y Salim，et al. Oncotarget. 2016，7(27): 41363-41379. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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