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Hydroxychloroquine Sulfate

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Cat.No：IH0720 Solarbio

CAS：747-36-4

Molecular Formula：C₁₈H₂₈ClN₃O₅S

Molecular Weight：433.95

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	747-36-4
Name	Hydroxychloroquine Sulfate
Molecular Formula	C₁₈H₂₈ClN₃O₅S
Molecular Weight	433.95
Solubility	Soluble in Water
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 212-019-3
MDL	MFCD00078203
SMILES	CCN(CCO)CCCC(NC1=CC=NC2=CC(Cl)=CC=C12)C.O=S(O)(O)=O
InChIKey	JCBIVZZPXRZKTI-UHFFFAOYSA-N
InChI	InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
PubChem CID	12947
Target Point	SARS-CoV;Autophagy;Toll-like Receptor (TLR)
Passage	Autophagy;Immunology & Inflammation
Background	Huperzine A is a reversible acetylcholinesterase (ACE) inhibitor.
Biological Activity	Hydroxychloroquine sulfate 是一种合成的抗疟疾药物，也可以抑制 Toll 样受体 7/9 (TLR7/9) 信号传导。[1-2]
Data Literature Source	[1]. Manzo C，et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6. [2]. Lamphier M，et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40
Unit	Bottle
Specification	50mg 100mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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