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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > ZCL-278CAS：587841-73-4
Molecular Formula：C21H19BrClN5O4S2
Molecular Weight：584.89
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 587841-73-4 |
| Name | ZCL-278 |
| Molecular Formula | C21H19BrClN5O4S2 |
| Molecular Weight | 584.89 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-256-5 |
| MDL | MFCD03623090 |
| SMILES | O=C(NC(NC1=CC=C(S(=O)(NC2=NC(C)=CC(C)=N2)=O)C=C1)=S)COC3=CC=C(Br)C=C3Cl |
| Target Point | Cdc42 |
| Passage | Cell Cycle |
| Background | ZCL278 is a selective Cdc42 modulator. |
| Biological Activity | ZCL278是一种有效的，选择性的 Cdc42 调节剂，直接结合到 Cdc42，且抑制其功能，Kd 为 11.4 μM。ZCL278 可抑制基于肌动蛋白的细胞功能，包括高尔基体组织和细胞运动。[1-2] |
| Data Literature Source | [1]. Friesland A，et al. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1261-6. [2]. Chou YY，et al. Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol. 2016 Apr 14;90(9):4494-510. |
| Unit | Bottle |
| Specification | 10mg 20mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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