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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > 10074-G5CAS：413611-93-5
Molecular Formula：C18H12N4O3
Molecular Weight：332.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 413611-93-5 |
| Name | 10074-G5 |
| Molecular Formula | C18H12N4O3 |
| Molecular Weight | 332.31 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00576774 |
| SMILES | O=[N+]([O-])C1=CC=C(NC2=CC=CC=C2C3=CC=CC=C3)C4=NON=C41 |
| Target Point | c-Myc |
| Passage | Apoptosis |
| Background | 10074-G5 is a c-Myc inhibitor. |
| Biological Activity | 10074-G5是c-Myc抑制剂，与c-Myc的bHLH-ZIP区域结合并使其变性（Kd=2.8 μM），因而抑制c-Myc/Max异聚体的形成和其转录活性（IC50=146 μM）。[1-2] |
| Data Literature Source | [1]. Yap JL，et al. Bioorg Med Chem Lett. 2013，23(1):370-4. [2]. Clausen DM，et al. J Pharmacol Exp Ther. 2010，335(3):715-27. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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