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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > A-966492CAS：934162-61-5
Molecular Formula：C18H17FN4O
Molecular Weight：324.35
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 934162-61-5 |
| Name | A-966492 |
| Molecular Formula | C18H17FN4O |
| Molecular Weight | 324.35 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD17215207 |
| SMILES | FC1=CC([C@H]2NCCC2)=CC=C1C3=NC4=C(C(N)=O)C=CC=C4N3 |
| Target Point | PARP1 2 |
| Passage | Cell Cycle;DNA Damage/DNA Repair; Epigenetics |
| Background | A-966492 is a potent PARP1 and PARP2 inhibitor. |
| Biological Activity | A-966492 是一种新颖的，有效的 PARP1 和 PARP2 抑制剂，Ki 值为 1 nM 和 1.5 nM[1]。 |
| Data Literature Source | [1]. Penning TD， et al. Optimization of phenyl-substituted benzimidazole carboxamide poly (ADP-ribose) polymerase inhibitors: identification of (S) -2- (2-fluoro-4- (pyrrolidin-2-yl) phenyl) -1H-benzimidazole-4-carboxamide (A-966492) ， a highly potent and efficacious |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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