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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > AC-PHSCN-NH2CAS：262438-43-7
Molecular Formula：C23H35N9O8S
Molecular Weight：597.64
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 262438-43-7 |
| Name | AC-PHSCN-NH2 |
| Molecular Formula | C23H35N9O8S |
| Molecular Weight | 597.64 |
| Solubility | Soluble in Water |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD30478885 |
| SMILES | O=C(N)C[C@@H](C(N)=O)NC([C@H](CS)NC([C@H](CO)NC([C@H](CC1=CNC=N1)NC([C@H]2N(C(C)=O)CCC2)=O)=O)=O)=O |
| Target Point | Integrin |
| Passage | Cytoskeleton |
| Background | AC-PHSCN-NH2 is a novel potent small peptide inhibitor of integrin α5β1 |
| Biological Activity | ATN-161 (Ac-PHSCN-NH2) is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.[1-2] |
| Data Literature Source | [1]. Stoeltzing O，et al. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer. 2003 Apr 20;104(4):496-503. [2]. Wang W，et al. The antiangiogenic effects of integrin alpha5beta1 inhibitor (ATN-161) in vitro and in vivo. Invest Ophthalmol Vis Sci. 2011 Sep 14;52(10):7213-20. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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