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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > BMH-21CAS：896705-16-1
Molecular Formula：C21H20N4O2
Molecular Weight：360.41
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to yellow Solid
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| CAS | 896705-16-1 |
| Name | BMH-21 |
| Molecular Formula | C21H20N4O2 |
| Molecular Weight | 360.41 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 809-833-1 |
| MDL | MFCD27225377 |
| SMILES | O=C(C1=CC=CN2C1=NC3=C(C=C4C(C=CC=C4)=C3)C2=O)NCCN(C)C |
| Target Point | DNA/RNA Synthesis |
| Passage | Cell Cycle;DNA Damage/DNA Repair |
| Background | BMH-21 is a novel DNA intercalator, which can bind to rDNA and inhibit the transcription of RNA polymerase I without phosphorylating histone H2AX. |
| Biological Activity | BMH-21是一种DNA嵌入剂，与核糖体DNA结合，并抑制RNA polymerase I (Pol I)转录。[1] |
| Data Literature Source | [1] Peltonen K，et al. Cancer Cell. 2014，25(1)，77-90. [2] Colis L，et al. J Med Chem. 2014，57(11)，4950-4961. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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