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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > CCT-245737CAS：1489389-18-5
Molecular Formula：C16H16F3N7O
Molecular Weight：379.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 1489389-18-5 |
| Name | CCT-245737 |
| Molecular Formula | C16H16F3N7O |
| Molecular Weight | 379.34 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD30489721 |
| SMILES | FC(F)(F)C(C=NC(NC1=CN=C(C#N)C=N1)=C2)=C2NC[C@H]3CNCCO3 |
| Target Point | Checkpoint Kinase (Chk) |
| Passage | Cell Cycle |
| Background | CCT245737 is a CHK1 inhibitor |
| Biological Activity | CCT245737 (SRA737, PNT-737) 是一种具有口服活性的CHK1抑制剂，IC50为1.4 nM。对CHK1的选择性比对CHK2和CDK1强1000倍以上。[1] |
| Data Literature Source | [1] Walton MI，et al. Oncotarget. 2016，7(3):2329-42. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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