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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > CFI-400945CAS：1338806-73-7
Molecular Formula：C33H34N4O3
Molecular Weight：534.65
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1338806-73-7 |
| Name | CFI-400945 |
| Molecular Formula | C33H34N4O3 |
| Molecular Weight | 534.65 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28386170 |
| SMILES | O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(/C=C/C5=CC=C(CN6C[C@@H](C)O[C@@H](C)C6)C=C5)=NN4)C1)NC7=C2C=C(OC)C=C7 |
| Target Point | Polo-like Kinase (PLK) |
| Passage | Cell Cycle |
| Background | CFI-400945 is a potent and selective PLK4 inhibitor. |
| Biological Activity | CFI-400945是一种具有口服活性的、有效的、选择性的PLK4抑制剂，Ki值为0.26 nM。[1] |
| Data Literature Source | [1] Sampson PB，et al. J Med Chem. 2015，58(1):147-69. [2] Yu B，et al. Eur J Med Chem. 2015，95:35-40. [3] Mason JM，et al. Cancer Cell. 2014，26(2):163-76. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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