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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > CK-636CAS：442632-72-6
Molecular Formula：C16H16N2OS
Molecular Weight：284.38
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 442632-72-6 |
| Name | CK-636 |
| Molecular Formula | C16H16N2OS |
| Molecular Weight | 284.38 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-256-5 |
| MDL | MFCD03036245 |
| SMILES | O=C(C1=CC=CS1)NCCC2=C(C)NC3=C2C=CC=C3 |
| Target Point | Arp2/3 Complex;Actin |
| Passage | Cytoskeleton |
| Background | CK-636 is an Arp2/3 complex inhibitor. |
| Biological Activity | CK-636是具有细胞渗透性的Arp2/3 复合体抑制剂，能抑制肌动蛋白的聚合，对人，裂殖酵母和牛的 IC50 值分别为4 μM，24 μM和32 μM[1]。 |
| Data Literature Source | [1]. Nolen BJ，et al. Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature. 2009 Aug 20;460(7258):1031-4. [2]. Kwon KW，et al. Migration of T cells on surfaces containing complex nanotopography. PLoS One. 2013 Sep 12;8(9):e73960 |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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