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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > INH-6CAS：1001753-24-7
Molecular Formula：C19H18N2OS
Molecular Weight：322.42
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1001753-24-7 |
| Name | INH-6 |
| Molecular Formula | C19H18N2OS |
| Molecular Weight | 322.42 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD04722622 |
| SMILES | O=C(NC1=NC(C2=C(C)C=C(C)C=C2C)=CS1)C3=CC=CC=C3 |
| Target Point | Hec1 |
| Passage | Cytoskeleton |
| Background | INH6 is a potent Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction and causes chromosomal abnormalities. |
| Biological Activity | INH6是有效的Nek2/Hec1抑制剂；抑制HeLa细胞生长的IC50值为2.4 μM[1]。 |
| IC50 | 2.4μM(HeLa)，1.7μM(MB231)，2.1μM(MB468)，2.5μM(K562)[1] |
| Data Literature Source | [1]. Qiu XL，et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem. 2009 Mar 26;52(6):1757-67. |
| Unit | Bottle |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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